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Dr. Mark S. Segal, MD, PhD

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Specializes in: Adult Nephrology

University of Texas Southwestern Medical School (1992)

Professional interests include: lupus nephritis, thrombotic thrombocytopenic purpura (TTP), glomerulonephritis, and more.

1600 Sw Archer Road
Gainesville, FL 32610

(352) 273-8815

Dr. Mark S. Segal, MD, PhD is a nephrologist in Gainesville, FL specializing in adult nephrology. He graduated from University of Texas Southwestern Medical School in 1992 and has 34 years of experience. Dr. Mark S. Segal, MD, PhD is affiliated with UF Health and FLORIDA CLINICAL PRACTICE ASSOCIATION INC.

Office Locations

1600 Sw Archer Road
Gainesville, FL 32610

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In The News (see more mentions in the news)

“"You're getting extra sugar, and there's no reason (for) rapid absorption of sodium because you're not sodium depleted," said Mark Segal, MD, PhD, a professor of nephrology at the University of...”—"Electrolyte Supplements Are Everywhere. Who Benefits From Them and When?", MedPage Today, March 2026

“"You're getting extra sugar, and there's no reason (for) rapid absorption of sodium because you're not sodium depleted," said Mark Segal, a professor of nephrology at the University of Florida...”—"It all started with Gatorade: Now electrolyte supplements are everywhere", The Washington Times, February 2026

“"You re getting extra sugar, and there s no reason (for) rapid absorption of sodium because you re not sodium depleted," said Mark Segal, a professor of nephrology at the University of Florida...”—"Electrolyte supplements are everywhere. Who benefits from them and when?", Washington Top News, February 2026

Medicare Procedure and Patient Information

2012 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2012 were hospital care, inpatient care, dialysis and lab tests.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	114
doctor visit	87
hemofiltration	23
hospital care	412
inpatient care	412
lab tests	77

Medicare Procedure and Patient Information

2013 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2013 were hospital care, inpatient care, dialysis and lab tests.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	161
doctor visit	105
hospital care	330
inpatient care	330
lab tests	93

2013 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	111
Female	125

**Ethnicity**
Non-Hispanic White	129
Black	90
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	61
From 75 to 84	0
85 and over	0
Less than 65	133

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2013

Hypertension	75
High Cholesterol	67
Stroke	17
Ischemic Heart Disease	64
Depression	50
Chronic Kidney Disease	75
Asthma	15
Osteoperosis	6
Atrial Fibrilation	25
Heart Failure	67
Chronic Obstructive Pulmonary Disease	32
Diabetes	59
Dementia	17
Cancer	8

Medicare Procedure and Patient Information

2014 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2014 were hospital care, inpatient care, dialysis and lab tests.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	148
doctor visit	117
hospital care	339
inpatient care	339
lab tests	74

2014 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	101
Female	128

**Ethnicity**
Non-Hispanic White	118
Black	99
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	68
From 75 to 84	0
85 and over	0
Less than 65	122

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2014

Hypertension	75
High Cholesterol	69
Stroke	11
Ischemic Heart Disease	62
Depression	45
Chronic Kidney Disease	75
Asthma	13
Osteoperosis	10
Atrial Fibrilation	21
Heart Failure	59
Chronic Obstructive Pulmonary Disease	29
Diabetes	52
Dementia	18
Cancer	11

Medicare Procedure and Patient Information

2015 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2015 were hospital care, inpatient care, lab tests and dialysis.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	65
doctor visit	112
hospital care	189
inpatient care	189
lab tests	77

2015 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	152
Female	204

**Ethnicity**
Non-Hispanic White	184
Black	140
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	112
From 75 to 84	0
85 and over	0
Less than 65	166

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2015

Hypertension	75
High Cholesterol	66
Stroke	16
Ischemic Heart Disease	57
Depression	40
Chronic Kidney Disease	75
Asthma	22
Osteoperosis	8
Atrial Fibrilation	16
Heart Failure	56
Chronic Obstructive Pulmonary Disease	30
Diabetes	57
Dementia	21
Cancer	10

Medicare Procedure and Patient Information

2016 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2016 were hospital care, inpatient care, dialysis and lab tests.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	97
doctor visit	96
hospital care	180
inpatient care	180
lab tests	78

2016 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	69
Female	106

**Ethnicity**
Non-Hispanic White	98
Black	66
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	61
From 75 to 84	0
85 and over	0
Less than 65	77

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2016

Hypertension	75
High Cholesterol	64
Stroke	14
Ischemic Heart Disease	61
Depression	47
Chronic Kidney Disease	75
Asthma	39
Osteoperosis	11
Atrial Fibrilation	19
Heart Failure	62
Chronic Obstructive Pulmonary Disease	36
Diabetes	54
Dementia	29
Cancer	8

Medicare Procedure and Patient Information

2017 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2017 were hospital care, inpatient care, lab tests and dialysis.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

blood draw	15
dialysis	77
doctor visit	95
hospital care	175
inpatient care	175
lab tests	80

2017 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	58
Female	88

**Ethnicity**
Non-Hispanic White	84
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	59
From 75 to 84	0
85 and over	0
Less than 65	61

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2017

Hypertension	75
High Cholesterol	61
Stroke	16
Ischemic Heart Disease	59
Depression	53
Chronic Kidney Disease	75
Asthma	13
Osteoperosis	11
Atrial Fibrilation	20
Heart Failure	54
Chronic Obstructive Pulmonary Disease	29
Diabetes	53
Dementia	31
Cancer	10

Medicare Procedure and Patient Information

2018 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2018 were hospital care, inpatient care, lab tests and dialysis.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

blood draw	22
dialysis	60
doctor visit	93
hospital care	149
inpatient care	149
lab tests	67

2018 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	67
Female	90

**Ethnicity**
Non-Hispanic White	87
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	50
From 75 to 84	0
85 and over	0
Less than 65	72

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2018

Hypertension	75
High Cholesterol	61
Stroke	16
Ischemic Heart Disease	57
Depression	45
Chronic Kidney Disease	75
Asthma	8
Osteoperosis	7
Atrial Fibrilation	24
Heart Failure	58
Chronic Obstructive Pulmonary Disease	35
Diabetes	52
Dementia	25
Cancer	11

Medicare Procedure and Patient Information

2019 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2019 were hospital care, inpatient care, lab tests and dialysis.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

blood draw	21
dialysis	43
doctor visit	98
hospital care	102
inpatient care	102
lab tests	68

2019 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	54
Female	79

**Ethnicity**
Non-Hispanic White	66
Black	55
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	46
From 75 to 84	0
85 and over	0
Less than 65	64

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2019

Hypertension	75
High Cholesterol	59
Stroke	15
Ischemic Heart Disease	53
Depression	40
Chronic Kidney Disease	75
Asthma	8
Osteoperosis	0
Atrial Fibrilation	20
Heart Failure	59
Chronic Obstructive Pulmonary Disease	31
Diabetes	47
Dementia	25
Cancer	11

Medicare Procedure and Patient Information

2020 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2020 were lab tests, hospital care, inpatient care and dialysis.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	12
doctor visit	73
hospital care	23
inpatient care	23
lab tests	24

2020 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	19
Female	52

**Ethnicity**
Non-Hispanic White	40
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	31
From 75 to 84	0
85 and over	0
Less than 65	29

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2020

Hypertension	75
High Cholesterol	49
Stroke	0
Ischemic Heart Disease	46
Depression	42
Chronic Kidney Disease	75
Asthma	0
Osteoperosis	0
Atrial Fibrilation	23
Heart Failure	42
Chronic Obstructive Pulmonary Disease	21
Diabetes	37
Dementia	18
Cancer	0

Medicare Procedure and Patient Information

2021 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2021 were hospital care, inpatient care, lab tests and dialysis.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

dialysis	11
doctor visit	55
hospital care	35
inpatient care	35
lab tests	34

2021 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	25
Female	43

**Ethnicity**
Non-Hispanic White	38
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	22
From 75 to 84	0
85 and over	0
Less than 65	31

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2021

Hypertension	75
High Cholesterol	62
Stroke	0
Ischemic Heart Disease	56
Depression	38
Chronic Kidney Disease	75
Asthma	0
Osteoperosis	0
Atrial Fibrilation	18
Heart Failure	49
Chronic Obstructive Pulmonary Disease	25
Diabetes	40
Dementia	19
Cancer	0

Medicare Procedure and Patient Information

2022 Medicare Procedure Volume

The top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL during 2022 were lab tests.

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

doctor visit	57
lab tests	47

2022 Medicare Patient Data

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	14
Female	36

**Ethnicity**
Non-Hispanic White	22
Black	0
Hispanic	0
Asian	0
Other	0
Native American	0

**Age**
From 65 to 74	13
From 75 to 84	0
85 and over	0
Less than 65	22

Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD in 2022

Hypertension	75
High Cholesterol	72
Stroke	0
Ischemic Heart Disease	34
Depression	34
Chronic Kidney Disease	75
Asthma	0
Osteoperosis	0
Atrial Fibrilation	30
Heart Failure	36
Chronic Obstructive Pulmonary Disease	26
Diabetes	30
Dementia	0
Cancer	0

Medicare Procedure and Patient Information

Average Medicare Procedure Volume From 2012 - 2022

Volume of procedures performed by Dr. Mark S. Segal, MD, PhD for Medicare patients.

The highest averages for the top procedures that Dr. Mark S. Segal, MD, PhD treated as a nephrologist in Gainesville, FL were hospital care, inpatient care, dialysis and lab tests.

blood draw	19
dialysis	78
doctor visit	89
hemofiltration	23
hospital care	193
inpatient care	193
lab tests	65

Average Medicare Patient Data From 2012 - 2022

Information about Medicare patients treated by Dr. Mark S. Segal, MD, PhD.

**Gender**
Male	60
Female	86

**Ethnicity**
Black / African American	40
Asian / Pacific Islander	0
Non-Hispanic White	78
Hispanic	0
Native American / Alaskan Native	0
Other	0

**Age**
75 to 84	0
85 and over	0
Less than 65	70
65 to 74	47

Average of Total of Conditions of Medicare patients treated by Dr. Mark S. Segal, MD, PhD From 2012 - 2022

The highest averages of the most common conditions of Medicare patients that Dr. Mark S. Segal, MD, PhD treated were chronic kidney disease, hypertension, high cholesterol and heart failure.

Hypertension	68
High Cholesterol	57
Stroke	9
Ischemic Heart Disease	49
Depression	39
Chronic Kidney Disease	68
Asthma	10
Osteoporosis	4
Heart Failure	49
Chronic Obstructive Pulmonary Disease	26
Diabetes	43
Atrial Fibrillation	19
Cancer	6
Dementia	18

Education & Training

Dr. Mark S. Segal, MD, PhD graduated from University of Texas Southwestern Medical School in 1992. He completed residency at Parkland Health & Hospital System. He is certified by the Internal Medicine - American Board of Internal Medicine and has a state license in Florida.

Medical School: University of Texas Southwestern Medical School (1992)

Residency: Parkland Health & Hospital System (1995)

Board Certification: Internal Medicine - American Board of Internal Medicine

Licensed In: Florida

Affiliations & Hospitals

Dr. Mark S. Segal, MD, PhD is associated with these hospitals and organizations:

UF Health

FLORIDA CLINICAL PRACTICE ASSOCIATION INC

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General Payments

These charts describe general payments received by Dr. Mark S. Segal, MD, PhD. Doctors may receive payments for a number of reasons, including meal compensation, travel compensation, and consulting.

**Payments by Company**
Alexion Pharmaceuticals, Inc.	$2,303 SOLIRIS $2,303
Takeda Pharmaceuticals U.S.A., Inc.	$150 GATTEX $150
Horizon Therapeutics plc	$132 KRYSTEXXA $132
Retrophin, Inc.	$90 $90
GENZYME CORPORATION	$77 $77
Other	$78 Gonal-f $64	Dialysis Products $14

**Types of Payments**
Consulting Fee	$1,125
Travel and Lodging	$1,036
Food and Beverage	$519
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program	$150

Research Payments

Dr. Mark S. Segal, MD, PhD has received 38 research payments totaling $194,040.

Biography

Dr. Mark Segal is an adult nephrology specialist in Gainesville, FL. He attended the University of Texas Southwestern Medical School and subsequently trained at Parkland Health & Hospital System for residency. Dr. Segal is especially interested in lupus nephritis, glomerulonephritis, and thrombotic thrombocytopenic purpura (TTP). He is affiliated with UF Health.